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Imdur (Isosorbide)

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Imdur is a medication used for heart-related chest pain, heart failure, and esophageal spasms. It can be used both to treat and to prevent heart-related chest pain. However, it is generally less preferred than beta blockers or calcium channel blockers.

Other names for this medication:
Aspitrate, Dilatrate, Ecosmin, Ismorin, Ismotic, Isoditrate, Isoloprin, Isordil, Isosorbide, Monit, Monoket, Monosprin, Nitren, Nitrofix, Nitroprin, Solosprin, Vasoprin

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Also known as: Isosorbide


Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). It does not work fast enough to relieve the pain of an angina attack that has already started.

Isosorbide mononitrate belongs to the group of medicines called nitrates. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. When used regularly on a long-term basis, this helps prevent angina attacks from occurring.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain isosorbide mononitrate. It may not be specific to Imdur ER. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This form of nitrate is used to reduce the number of angina attacks over a long time. It will not relieve an attack that has already started because it works too slowly. The extended-release form gradually releases medicine to provide its effect for 8 to 10 hours. Check with your doctor if you also need a fast-acting medicine to relieve the pain of an angina attack.

You should take this medicine first thing in the morning and follow the same schedule each day. This medicine works best if you have a "drug-free" period of time every day when you do not take it. Your doctor will schedule your doses during the day to allow for a drug-free time. Follow the schedule of dosing carefully so the medicine will work properly.

Swallow the extended-release tablet whole with a half glass of water. Do not split, crush, or chew it.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For prevention of angina: For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Take the dose in the morning right after you wake up. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—20 milligrams (mg) two times a day. Take the first dose in the morning right after you wake up, and the second dose 7 hours later. Children—Use and dose must be determined by your doctor.


If you overdose Generic Imdur and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Imdur are difficult or slow breathing, muscle cramps, nausea, vomiting, diarrhea, high temperature, fainting, abnormal heartbeat, changes in vision, flushing, convulsions, severe throbbing migraine, lightheadedness.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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Dermatotoxicology of sulfur mustard: Historical perspectives from World War I. This study indicates that, despite the high prevalence of POAG, MYOC mutations are rare in the African American population. Capecitabine-based treatment of a patient with a novel DPYD genotype and complete dihydropyrimidine dehydrogenase deficiency. Further development of LA test with other serotypes is necessary. Optimal diagnostic thresholds were determined for DSM-IV attention deficit hyperactivity disorder, and the psychometric properties were compared to alternative definitions. The pathological characteristics was in accordance with GVHD in 5 cases. Global suicide mortality rates - a light at the end of the tunnel?. Although the left ventricular (LV) end-systolic pressure-dimension relation is a load-independent, sensitive index of contractile state bystolic 10mg tab , its accurate determination requires afterload manipulation.

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The objective of this study was to examine the effect of thoracic epidural anesthesia (TEA) on left ventricular systolic and diastolic function assessed by transesophageal echocardiography under general anesthesia. Echocardiographic Detection of Intramyocardial Coronary Obstruction Produced by Pericardial Hydatid Cyst. Post-mortem glycosylated hemoglobin (HbA1c): evidence for a history of diabetes mellitus. The relationship between environment, efficacy beliefs, and academic achievement of low-income African American children in special education. Choosing sides: HIV health care practices among shared populations of HIV-positive Latinos living near the US-Mexico border. Although free DOX showed to be more effective at killing the human cervical cancer cells (HeLa) over human breast adenocarcinoma cancer cells (MDA-MB-231), the DOX-loaded rGO/dopa-MAL-c (RGDfC) nanostructure showed an opposite effect being notably more effective at targeting and killing the MDA-MB-231 cells. Although atypical in location, spindle cell lipoma should always be kept in differential diagnosis of a newly-noted soft tissue mass, as this entity may be easily cured by simple excision. Tubocurarine has no clear effect on the metabolism of exogenous arachidonic acid in hamster isolated lungs.

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Clinical stages were determined by the presence or absence of varices, ascites, and variceal hemorrhage. In a definite range of burn size, Meek skin grafting has a lower therapeutic cost and better therapeutic effects as compared with micrografting. The aim of this study was to evaluate the incidence of acute kidney injury (AKI) and identify the relationship between AKI and the prognosis of patients with acute myocarditis. To elucidate the contribution of bcl-2 and bax proteins to epidermal differentiation and skin carcinogenesis, we investigated keratinocyte proliferation, differentiation and tumourigenesis in bcl-2(-/-) and bax(-/-) mice. The patient often presents with cool and mottled skin, and with severe pain from the umbilicus to the lower extremities. The sequence diversity of the integrase genes in these clones was sufficient to classify them within three new classes of integron. With the methodological quality of the included studies on functional recovery and the small number of studies on bladder dysfunction taken into consideration, further rigorous studies prove needed.

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It is difficult to treat the PTA patients with IAA, intra-mural coronary artery or mechanical ventilation support before operation. Together, these findings suggest that hemilateral and generalized pain control mechanisms are disrupted in CRPS, and that multisensory integrative processes are compromised. Despite an abundance of literature on severe injuries that can be treated with salvage or amputation, the appropriate management of these injuries remains uncertain. This conceptual account is buttressed by empirical findings from 6 studies that show the effects of hypothesized emotional, cognitive, and motivational determinants of regulation choice (Studies 1-3) and illuminate the mechanisms that underlie choices between different emotion regulation strategies (Studies 4-6). In the last years an in vitro cytotoxicity assay for the testing of industrial waste waters with the permanent fish cell line RTG-2 was established and pre-validated as an alternative to the fish test with the golden orfe. Does white coat hypertension require treatment over age 80?: Results of the hypertension in the very elderly trial ambulatory blood pressure side project. The life-time of DNA/membrane complex formation is of the order of 1 s and has to be taken into account to improve protocols of electro-mediated gene delivery. The ribbon matching problem involves a double application of the assignment algorithm. The author has presented a case report of a patient who was struck by lightning and exhibited extensive soft tissue injury with myoglobinuria.

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