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Lasix (Furosemide)
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Lasix

Lasix is a loop diuretic (water pill) that makes you urinate more. It works in the kidneys to get rid of extra water and electrolytes, which helps with swelling and lowers blood pressure. Lasix can be taken once or twice a day for swelling. Adults typically start with 20 mg to 80 mg per dose. Some adults with really bad swelling problems may take up to 600 mg in a day.

Other names for this medication:
Aldalix, Anfuramide, Ansemid, Betasemid, Foliront, Frusemide, Frusenex, Furantral, Furesis, Furetic, Furide, Furocot, Furosemide, Furovet, Furoxem, Furozenol, Fursemid, Furtenk, Fusix, Inclens, Intermed, Jufurix, Lasilacton, Lasilactone, Lasiletten, Lasilix, Salix, Vesix

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Also known as: Furosemide

Description

Lasix is indicated in adults, infants and children for the treatment of oedema associated with congestive heart failure, cirrhosis of the liver and renal disease including the nephrotic syndrome. Lasix is particularly useful when an agent with greater diuretic potential than that of those commonly employed is desired. Parenteral therapy should be reserved for patients unable to take oral medication or for patients in emergency clinical situations.

Lasix Injection is also indicated as adjunctive therapy in acute pulmonary oedema and cerebral oedema where intense and rapid onset of diuresis is desired. If gastrointestinal absorption is impaired or oral medication is not practical for any reason, Lasix is indicated by the intravenous route. Parenteral use should be replaced with oral Lasix as soon as practical.

Dosage

This section provides information on the proper use of a number of products that contain furosemide. It may not be specific to Lasix. Please read with care.

A nurse or other trained health professional will give you or your child this medicine in a hospital. This medicine is given as a shot into a muscle or a vein.

Your doctor will give you a few doses of this medicine until your condition improves, and then switch you or your child to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Detailed Lasix dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include feeling very thirsty or hot, heavy sweating, hot and dry skin, extreme weakness, or fainting.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Lasix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Excessive diuresis may result in dehydration and reduction in blood volume with circulatory collapse and with the possibility of vascular thrombosis and embolism, particularly in elderly patients.

Excessive loss of potassium in patients receiving cardiac glycosides may precipitate digitalis toxicity.

In patients with hepatic cirrhosis and ascites, initiation of therapy with Lasix is best carried out in hospital. Sudden alterations of fluid and electrolyte balance in patients with cirrhosis may precipitate hepatic coma, therefore, strict observation is necessary during the period of diuresis.

Cases of reversible or irreversible tinnitus or hearing impairment have been reported. Usually, reports indicate that Lasix ototoxicity is associated with rapid injection or infusion, severe renal impairment, hypoproteinaemia, doses exceeding several times the usual recommended dose, or concomitant therapy with aminoglycoside antibiotics, ethacrynic acid, or other ototoxic drugs. In patients with hypoproteinaemia, e.g. associated with nephrotic syndrome, the effect of Lasix may be weakened and its ototoxicity potentiated. Cautious dose titration is required. If the physician elects to use high dose parenteral therapy, controlled intravenous infusion is advisable (for adults with normal renal function, an infusion rate not exceeding 4 mg Lasix per minute must be used; for adults with impaired renal function, an infusion rate of no greater than 2.5 mg per minute must be used).

Caution should be exercised when administering curare or its derivatives to patients undergoing frusemide therapy. It is also advisable to discontinue frusemide for one week prior to any elective surgery.

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Plasma concentrations of inhibin A and inhibin B during pregnancy and early lactation in chimpanzees were determined by enzyme-linked immunosorbent assay (ELISA). CD98 induces LFA-1-mediated cell adhesion in lymphoid cells via activation of Rap1. The content of VIP mRNA was measured in the SCN in fetuses at the 21st embryonic day (E21) and in postnatal rats at day 11 (P11) following chronic depletion of serotonin by p-chlorophenylalanine, an inhibitor of serotonin synthesis. Ruby and diode lasers may have a long-lasting effect (one year), but this, however, must be further clarified. In fact, HIV-1 PR efficiently blocks cap- and poly(A)-dependent translation initiation in HeLa extracts. Biodegradation of malachite green by Brevibacillus laterosporus MTCC 2298.

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Reduced work ability in middle-aged men with asthma from youth--a 20-year follow-up. RJC was effective in improving insulin resistant, which may be one of the mechanisms of its therapeutic effect on CHD. Enhanced muscle insulin receptor autophosphorylation with short-term aerobic exercise training. To mark the 20th anniversary of this finding, the leaders of the three research teams have written personal essays describing the events leading up to the discovery in each of their laboratories. WNT4 mRNA and protein were present in human ovaries throughout fetal development and in different follicular stages in adult ovaries. Biologic properties of non-antibiotic, chemically modified tetracyclines (CMTs): a structured, annotated bibliography. In the present study, we have extended our work to investigate the expression pattern of other components in the HD complex, namely, BPAG2, ITGalpha6 and ITGbeta4 in three distinct biological groups of nasopharyngeal epithelial cells: (a) non-malignant nasopharyngeal epithelial cells established from primary culture of nasopharyngeal explants, (b) non-malignant nasopharyngeal epithelial cells immortalized by viral oncogenes, SV40 or HPV16E6E7, and (c) nasopharyngeal carcinoma (NPC) cells. The presence of concurrent illnesses and nutrition-related metabolic complications were also associated with longer hospitalization length (by 2.1 and 2.4 days, respectively). The Joint Pharmaceutical Analysis Group meeting on the Analysis of Inhaled Products, held in London, included topics covering new developments in the field of inhalation therapy.

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Molecular determinants of adaptation of highly pathogenic avian influenza H7N7 viruses to efficient replication in the human host. Characteristically, the tachycardia cycle length changed suddenly depending on the bundle branch used in retrograde direction. A clinicopathologic study of minimally invasive follicular carcinoma of the thyroid gland with a review of the English literature. We aim to assess the association between CS itself (without medical indications) and risk of childhood asthma. Protein expression of GLUT4 (major isoform) and GLUT12 (one of the most recently discovered isoforms) were measured can i cut my norvasc pill in half by Western blotting in multiple AT depots, as well as AS160 (a potential key player in GLUT trafficking pathway). marinus chromosome contains a single rRNA operon with a 16S-23S intergenic region coding for tRNA(Ile) and tRNA(Ala). Yet, there is limited evidence regarding the integration of palliative care for this client group. Previously known splicing alterations were consistently detected, occasionally with a more complex splicing pattern than expected.

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