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Trileptal (Oxcarbazepine)
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Trileptal

Trileptal is an anticonvulsant. It works by decreasing nerve impulses that cause seizures and pain. Trileptal is used either alone or with other medicines to treat partial seizures. Trileptal is used with other medicines in adults and children who are at least 2 years old.

Other names for this medication:
Carbamac, Carbox, Mezalog, Oleptal, Oxamazetol, Oxcarb, Oxcarbazepine, Oxcazo, Oxepin, Oxeptal, Oxetol, Oxital, Oxmazetol, Oxpine, Oxrate, Oxycarb, Oxzey, Seizurone, Selzic, Zenoxa, Zepox

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Also known as: Oxcarbazepine

Description

Trileptal is used for treating certain types of seizures in patients with epilepsy. It may be used alone or in combination with other medicines. It may also be used for other conditions. Trileptal is an anticonvulsant. It works by slowing abnormal nerve impulses in the brain. Trileptal is also known as Oxcarbazepine, Trexapin.

Dosage

Trileptal may be taken with or without food. It is important to take all doses on time to keep the level of medicine in your blood constant. Take doses at evenly spaced intervals. Do not skip doses. Taking Trileptal at the same times each day will help you to remember to take it. Continue to take Trileptal even if you feel well. Do not miss any doses. Trileptal works best when there is a constant level of Trileptal in your body. If you want to achieve most effective results do not stop taking Trileptal suddenly. If Trileptal is stopped, this should be done gradually. The risk of seizures may be increased if Trileptal is suddenly stopped.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Store in the original container. Use within 7 weeks of first opening the bottle. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Trileptal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Trileptal if you are allergic to its components. Do not take Trileptal if you are pregnant, planning to become pregnant, or are breast-feeding. If you have a history of seizures, you may suddenly lose consciousness while you are taking Trileptal. Avoid activities where loss of consciousness could be dangerous to you or others (driving, swimming, climbing, and operating heavy machinery). Hormonal birth control pills may not work as well while you are using Trileptal. To prevent pregnancy, use an extra form of birth control (condoms). Trileptal may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Trileptal. Use a sunscreen or wear protective clothing if you must be outside for more than a short time. Trileptal must be gradually decreased when discontinued. Talk to your health care provider about the proper way to stop Trileptal. Notify your health care provider if seizure control worsens. Lab tests, including sodium blood levels, may be performed while you use Trileptal. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. Trileptal should not be used in children younger than 2 years old. Safety and effectiveness in these children have not been confirmed. Avoid alcohol. It can be dangerous to stop Trileptal taking suddenly.

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Findings indicate that access to adequate mental health services, not just recovery-oriented and peer support services, is not widely available for this population, largely due to communication barriers. Functional reconstruction with an extended supraclavicular fasciocutaneous island flap following ablation of advanced oropharyngeal cancer. The number, distribution of patients, and mortality rates of patients who sustained burn injury from the years 1985-2006 were assessed using administrative hospital data obtained from the New York State Department of Health. Structure and function of the mucous membrane of the stomach and duodenum in workers in the aluminum industry. Hyaluronan incorporation into model contact lens hydrogels as a built-in lubricant: Effect of hydrogel composition and proteoglycan 4 as a lubricant in solution. Information pick-up by infants: what is it, and how can we tell?. Australian New Zealand Clinical Trials Registry ACTRN12613001207707. Use of a Dirichlet prior over parameters and Gibbs prior over structure can greatly reduce the over-fitting in the new model. The MMH-NTO mixture has more reaction channels than EtOH-NTO based on statistical analyses of chemical reaction events and channels at early stages of the dynamics. Both molecules are highly expressed in the central nervous system (CNS), though RPTPgamma is distributed also in several peripheral tissues.

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Coagulation testing with the Du Pont aca discrete clinical analyzer. One particularly challenging obstacle to successful IVC filter retrieval is the formation of a radiolucent fibrin cap over the embedded apex of the IVC filter. Cystic kidney disease and diabetes--an underdiagnosed monogenic developmental disorder. In a study of 71 undergraduates, abortion attitudes were not associated with sex and, for the females, only weakly with masculinity scores. Polyethylene glycol improves conjugation of bovine hemoglobin and human serum albumin in a controlled ratio. Pathological conditions of the nose giving rise to ophthalmic disorders. We conducted a meta-analysis to assess the association between TNFA gene TNFA-308(G/A), TNFA-238(G/A), TNFA-863(C/A), TNFA-857(C/T), TNFA-1031 (T/C) polymorphisms and HCC susceptibility. Interparticle migration of metal cations in stream sediments as a factor in toxics transport. Retrospective analysis on the types of mid and late stage of laryngeal carcinoma clinical material, 22 patients supracricoid partial laryngectomy-cricohyoidopexy, 20 patients horizontal-vertical hemilaryngectomy, each with the added radiotherapy.

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A systematic review of built environment factors related to physical activity and obesity risk: implications for smart growth urban planning. Meta-analysis of the relationship between polymorphisms of 399 point of X-ray repair cross complementing gene group 1 and hepatocellular carcinoma. In the present multi-step reaction, PtCl(2) likely plays dual roles: as the catalyst for the rearrangement of propargyl alcohols to the corresponding alkenyl ketones and as the catalyst for the addition of indoles to the alkenyl ketones. Hepatic mesenchymal hamartoma (HMH) is the second most common benign hepatic tumor in children. A comparative study of misfit profiles was performed for the most common clinical situations in mouth rehabilitation procedures with fixed restorations: gold-cast DB and porcelain metal alloy DB. These data, which are based on genetic variants used for etiologic research, confirm previous evidence of group-specific variation, while underscoring the limited magnitude of this variation.

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Patients were examined using either a 1.5 Tesla or a 3 Tesla MRI. 460 stools specimens were collected from children with acute diarrhea cured in the childrens, hospital of Changchun in 2010. A cDNA clone, EICBP (Ethylene-Induced CaM Binding Protein), encoding a protein that interacts with activated CaM was isolated in this screening. Monoclonal antibody (MoAb)-based therapies have opened innovative treatment avenues that have impacted on the management of patients with both neoplastic and non-neoplastic hematological diseases. Gross structural change of the heart chambers is directly reflected at the cellular level by altering the morphological characteristics of individual cardiomyocytes. An ideal biomarker for sleep should change rapidly with sleep onset, remain at a detectably differential level throughout the sleep period, and exhibit a rapid change with waking. Using design principles to foster understanding of complex health concepts in consumer informatics tools. Early tumor shrinkage indicates a favorable response to bevacizumab-based first-line chemotherapy for metastatic colorectal cancer. Evaluation of beta-cell sensitivity to glucose and first-phase insulin secretion in obese dogs.

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A 3 Tesla MRI system (Intera, Philips Medical Systems, Best, The Netherlands) was used to acquire T1w spin-echo (T1 SE), T1w turbo spin-echo (T1 TSE) and T1w gradient-echo (T1 GRE) sequences in axial orientation. Besides the established risk factor remission status after induction, result of positron emission tomography before and after transplant was the most important prognostic factor for progression-free survival and overall survival. Potential usefulness of an EPA-enriched nutritional supplement on chemotherapy tolerability in cancer patients without overt malnutrition. Concerted action of the ribosome and the associated chaperone trigger factor confines nascent polypeptide folding. Then, deep reactive ion etching is used to hierarchically create nanostructures on the microstructures using the Cr nanodots as an etch mask. Those not detected were norepinephrine, homovanillic acid, and 5-hydroxytryptamine. Combined analysis of chromosomal aberrations and glutathione S-transferase M1 and T1 polymorphisms in pathologists occupationally exposed to formaldehyde. The degree of this depressive effect was somewhat dependent on the stimulus intensity applied to the somatic afferent nerves. Using surface plasmon resonance, we show that the S249D mutation weakens the binding affinity and changes the kinetics of 4.1-ERM to PIP(2) binding.

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The study investigated the effects of the integral continual jejunal interposition, the Billroth I and Billroth II operations, and the isolated jejunal interposition following subtotal distal gastrectomy on the blood glucose, insulin, routine blood parameters, liver function, and myoelectrical activity in Beagle dogs. Fieldwork was conducted over five consecutive school days at each school. In the absence of the drug, MVC-Res Env maintains a highly efficient interaction with CCR5, similar to that of MVC-Sens Env, and displays a relatively modest increase in dependence on the CCR5 N terminus. This is the first in vivo deficiency analysis of a member of the SR protein family. hyodysenteriae B204 sucrase activity cleaved sucrose and, to a lesser extent, raffinose and had a pH optimum of 5.7 to 6.2. We demonstrate that PHS induces activation of the calcium-dependent kinase CPK3, which phosphorylates its binding partners, the 14-3-3 proteins. Performance factors in associative learning: assessment of the sometimes competing retrieval model.

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Although endoscopic retrograde cholangiopancreatography alone could show the maljunction in this case, simultaneous IDUS will be useful in making an accurate diagnosis of AAPBDS. Neither mixed susceptibility nor mixed genotype was found in clarithromycin resistant strains. Additionally, we also evaluated fully fertile strains with genotypes very close to that of QM6a in order to distinguish between strain-specific and fertility-specific characteristics. The aim of the present cross-sectional study was to examine work- and nonwork- related factors and physical and mental health outcomes associated with combined time- and strain-based work-life conflict (WLC) among adult employees living and working in Switzerland as well as possible gender differences in this regard. The Koach project suggests that patients, therapists, and objective outcome measures differ significantly in their assessments of the usefulness of therapy.

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Patterns of dental development in Homo, Australopithecus, Pan, and Gorilla. However, the radiation delivered is considerable, and the gonads cannot be shielded effectively. Profiling these specific markers may contribute to better understanding of the clinical conditions in individual patients and their pathogenesis. Genetic, transcriptional, and biochemical studies demonstrated that anaerobic growth recovery by the NarXL mutant was the result of NapAB periplasmic nitrate reductase expression. In the mechanically ventilated patient, externally generated aerosols have very poor lung delivery because the endotracheal tube functions as a barrier to aerosol passage.

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Histopathological examination of the lungs revealed that sST2-Fc over-expression markedly suppressed allergen-induced peribronchial inflammation and disruption of the alveolar architecture. Protective effect of the tachykinin NK2 receptor antagonist nepadutant in acute rectocolitis induced by diluted acetic acid in guinea-pigs. Two different doubly H-bonded motifs were investigated in carbon tetrachloride, chloroform, 1,1,2,2-tetrachloroethane, and cyclohexane, and the results were similar in all cases, with effective molarities of 3-33 M for formation of intramolecular H-bonds. Study treatment consisted of gemcitabine 1000 mg/m(2), i.v., as 30 min-infusion, days 1 and 8 every 21 days, plus oral capecitabine 830 mg/m(2) b.i.d., days 1-14 every 21 days. On the basis of the GC peak areas of those 14 markers, a cluster analysis was carried out, resulting in three clusters, each corresponding to a given P-2-P synthesis route.

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Cancer incidence rates in Turkey in 2006: a detailed registry based estimation. Risk factors related to renal disorders in HIV-1 infected patients. The component on the higher energy side of this peak through 1s excitation into a Rydberg orbital produces resonant Auger decays in which the excited Rydberg electron moves into a slightly higher Rydberg orbital, or is partly shaken up to a significantly higher Rydberg orbital. Determination of immunoglobulins in blood serum by high-performance affinity chromatography. The expression of angiogenic factors in tumors is controlled by both intrinsic factors in the tumor cell and the influence of the host microenvironment. Thymic epithelial cells responsible for impaired generation of NK-T thymocytes in Alymphoplasia mutant mice. Embracing a healthy community agenda can create fruitful new partnerships and increase the impact on systemic change. The only antigenemia positive BMT recipient was found negative for CMV mRNA, but positive in all other tests. Temperature dependence of the electrophoretic mobility of multilamellar liposomes prepared from dimyristoylphosphatidylcholine was measured in the presence of salts with different anions in aqueous solutions. A series of wild-type or mutant recombinant H3P chains produced with a mouse cDNA expressed in Escherichia coli allowed us to demonstrate that this domain binds HA in a noncovalent fashion.

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When symptomatic, they present with features of radiculopathy, myelopathy, or vertebral fractures. Bulk electroporation and population calcium imaging in the adult mammalian retina. On histopathological evaluation, features such as lymphocytic exocytosis, and dermal infiltrate of eosinophils, lymphocytes and histiocytes were seen in a significantly greater number of drug exanthems. Saving resources: avian influenza surveillance using pooled swab samples and reduced reaction volumes in real-time RT-PCR. Cyclooxygenase (COX)-1 and COX-2 catalyze the formation of prothrombotic and antithrombotic eicosanoids, respectively.

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Development of an agile knowledge engineering framework in support of multi-disciplinary translational research. These data suggests that the sleeping brain can process auditory stimuli and detect meaningful events. JmjC: cupin metalloenzyme-like domains in jumonji, hairless and phospholipase A2beta. Anderson Cancer Center successfully integrated physician assistants into patient care services, as judged by an overall increase in departmental productivity, broadened patient care coverage, and physician satisfaction with midlevel services. Possible modulation by male sex hormone of Th1/Th2 function in protection against Plasmodium chabaudi chabaudi AS infection in mice. The mechanical and biochemical content of mature bovine and canine explants were not significantly affected by the presence of dexamethasone and maintained what is a high dose of zofran initial (day 0) mechanical and biochemical properties throughout the entire culture period with or without supplementation of dexamethasone. As a result nowadays it is possible to find available commercial products for cardiovascular personal healthcare monitoring. When absorption of phosphate is blocked by sevelamer or cellular uptake is inhibited by phosphonoformic acid (PFA), larval development is delayed in a phosphate-dependent fashion. In recent years some researchers have reported studies establishing this association in different types of cancer. Since for many of these substances, only limited or no toxicological data are available, the development of alternative methodologies to establish rapidly and cost-efficiently level of safety concern is critical to ensure adequate consumer protection.

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We report our finding from a 5-year review of our experience with sliding genioplasty. Radioisotopic ultram dosing study of platelet kinetics can provide a preliminary orientation in the diagnosis of thrombocytopenia. Advanced age is an independent predictor for increased morbidity and mortality after emergent surgery for diverticulitis. This study was undertaken to assess the status of iodine deficiency disorders control and prevention after 10 years of implementation of USI in a severe iodine deficiency region in China. Here we report that expressions of hCRM1 in murine cells resulted in marked increases in the production of infectious HIV-1 and feline immunodeficiency virus (FIV).

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The development of new, specific models derived from fetuses with CDH could improve the accuracy of WE for infants with this condition. Consistent comments from the focus groups combined with those from cognitive debriefing interviews led to the incorporation of 14 finalized attributes into the Experience with Allergic Rhinitis Nasal Spray Questionnaire (EARNS-Q) items. These MRSA isolates mostly belonged to sequence type 398 (ST398). In contrast, RV collagen accumulation was potentiated during the initial weeks but not during chronic aortocaval shunt. did not decrease, but transcription of fdh increased when after 249 days molybdenum, tungsten and selenium were supplied to the reactor feed. Antihistamine drugs in treatment of nausea and vomiting due to streptomycin. Subsequently increased apoptosis and decreased proliferation mediated by cytochrome c was noted and this was reversed by CsA. We report the first case of a child, as far as we know, with neurofibromatosis type I and subarachnoid hemorrhage bactrim 400 80 mg caused by rupture of an arteriovenous malformation. The analysis was carried out at national, county and dental district level based on the annual census reports from public dental officers.

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The organisms were isolated in minor numbers from coastal water samples from five of 12 bathing areas around Funen at the end of July, but not at the end of November. We previously identified a number of genes which were methylated significantly more frequently in the tumor compared to the non-cancerous lung tissues from non-small cell lung cancer (NSCLC) patients. We created a Cultural Assimilation Scale (CAS) using 8 questions assessing the degree of Japanese identity and lifestyle compared to a Western one. Paraderris elliptica may contain several cryptic lineages that need further investigation. Implants with 32P-foils for LDR-brachytherapy of benign stenosis in urology and gastroenterology. We examine the time evolution of states created by the nonadiabatic interaction of a polar molecule with combined electrostatic and pulsed nonresonant adhd medication floxin laser fields and show that the orientation due to the electrostatic field alone can be greatly enhanced by restricting the angular amplitude of the molecule by the pulsed laser field.

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Motor and phosphene thresholds: a transcranial magnetic stimulation correlation study. Fractal, entropic and chaotic approaches to complex physiological time series analysis: a critical appraisal. The angiogenic process is controlled by variety of factors of which the vascular endothelial growth factor (VEGF) pathway plays a major role. In this paper, the authors offer their experiences in the neuroendoscopic management of this uncommon type of hydrocephalus. Apoptotic events in a human ovarian cancer cell line exposed to anthracyclines. Our structural model of the RING domain provides a starting point for further structure-function analysis of this critical region of the protein. Cloning and in-depth studies of the pikromycin biosynthetic gene cluster from Streptomyces venezuelae have led to new avenues in modular polyketide synthases, deoxysugar biosynthesis, cytochrome P450 hydroxylase, secondary metabolite gene regulation, and antibiotic resistance.

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A total of 485 patients were enrolled, from whom 352 suspicious, adequate biopsy specimens were collected. The multiple mini-interview (MMI) has been shown to be a valuable tool to aid the selection of medical students. Creating an environment where staff nurses use critical thinking skills and access their advanced practice nurse (APN) resources as they do their work has been a win-win-win situation for the patients, the hospital, and the college at the health science center. Mono-, di- and trisaccharide representing the reducing terminal of the core structure of N-glycans were incorporated into Leu-Lys-Asn-Gly-Gly-Pro hexapeptide that is a partial structure of the Trp-cage mini-protein by linear assembly. Both context insensitive disclosure and context insensitive avoidance may hamper interpersonal support and fuel the problem. The Parent-Child Relationship in the Treatment of Elderly Psychiatric Patients. Rural clinical experiences for emergency medicine residents: a curriculum template. The statin effect was reversed by mevalonate and geranylgeranyl-pyrophosphate and mimicked by the Rho inhibitor C3 transferase, indicating the involvement of Rho in the signal transduction pathway leading to COX-2 expression. Hormonal hypertension and nephrosclerosis as influenced by the diet. Scraped cervical cell specimens were also collected from 50 women with precancerous and cancerous lesions of the uterine cervix.

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This procedure seems to be helpful to improve denture function, especially in the mandible, in patients who cannot be treated with implants. Technique for central aortic cannulation in extensive aortic dissection. This mechanistic basis of resistance in a vertebrate population provides evidence of evolutionary change due to selective pressure at a single locus. coli of serogroups O139:K12 and O141:K85a,b but not of serogroup O149:K91:F4a,c. After surgery for lung cancer, patients may be referred for adjuvant chemotherapy. Prospective studies that incorporate early autism screening and autism diagnostic testing are needed to better delineate the sensitivity and specificity of early signs of autism in ex-premature children. These results could support the notion that hASCs differentiation into neuron-like cells represents a regulated process analogous to what occurs during neuronal differentiation of NSCs and could partially contribute to elucidate the molecular mechanisms involved in neuronal differentiation of adult human nonneural tissues. In dogs with PDH, twice-daily administration of low-dose trilostane is an effective approach to the management of PDH.

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Pathways from sexual stigma to incident HIV and sexually transmitted infections among Nigerian MSM. At 24h number of cells adhered to the three kind of surfaces was similar, but during the following three days, cells seeded on S-SLA and on SS proliferated to a greater extent than those cultured on H-SLA. Importantly, the data show clear evidence for previously unreported product inhibition for the LuxAB reaction. Use of this approach to enhance delivery of monoclonal antibodies has proven fruitful. tRNA(leu)(CAG) and tRNA2(arg)(TCG) are abundant in the cytosol, but relatively scarce in mitochondria. Investigation of the use of three electroencephalographic electrodes for long-term electroencephalographic recording in awake and sedated dogs. Using phylogenetic generalized least-squares regression, we find that the correlation between chromosome number and genome size in the genus grades from flat or weakly positive at fine phylogenetic scales to weakly negative at deeper phylogenetic scales.

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Twenty-five pancreatic neuroendocrine neoplasms in 22 patients underwent preoperative dynamic CT. A number of minimally invasive technologies exist for the treatment of prostate cancer (CaP), each with their associated morbidities. The purpose of the present study was to evaluate the awareness about antibiotic resistance by investigating the practice in a group of self-medication users in a sample of adults in Romania and the variables associated with such practice. To evaluate the impact of multivessel disease (MVD) with and without a chronic total occlusion (CTO) on early and late mortality in ST-elevation myocardial infarction protonix drug class (STEMI) patients with and without cardiogenic shock (CS). We report the successful surgical closure after failed endoscopic treatment, of a gastro-tracheal fistula following esophago-gastrectomy for cancer after induction chemo-radiotherapy. A pull-down method with a biotinylated bait protein prepared by cell-free translation using a puromycin linker.

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The direct correlation between the 2 systems is established suggesting that head and neck oncologists may communicate accurately, thus allowing optimal treatment for the patient to be selected. Presenting data versus predictions as basic scientific information: target-controlled infusions versus microgram per kilogram per minutes. For instance, it has been demonstrated that the antigenic density of the targeted molecule at the tumor cell surface is an important factor. The Prandtl-Ishlinskii (PI) operator can model hysteresis well, albeit a major inadequacy: the inverse operator does not exist when the hysteretic curve gradient is not positive definite, i.e., ill condition occurs when slope is negative. In addition, we researched transcriptome changes during different periods of regeneration by using a tag-based digital gene expression (DGE) system. Winter accumulation of acidic pharmaceuticals in a Swedish river. Extreme autistic traits are substantially genetically independent of intellectual disability. Similarly, downregulation of BRCA1 protein expression is observed in the majority of basal-like breast cancers. The analeptic action of lysergic acid diethylamide on reserpinesedated mice. This suggests that mindfulness training may lead to an enhanced emotional experience coupled with the ability to recovery quickly from negative emotional states.

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